Abstract
The functional state of microvascular blood flow is the major pathogenic determinant in patients with intermittent claudication (IC). Revealing features of microcirculation (MC) shifts has been especially valuable after endovascular interventions. Purpose. To assess the alterations in MC profile after the restoration of main blood flow to affected extremity in patients with IC. Material and methods. MC was assessed by laser Doppler flowmehy in 37 patients before and 1 month after lower extremity angioplasty. Results. Restoration of main blood flow was associated with increased nutritional blood flow by 56.0 %, decreased arteriole-venule shunts by 30.7 % and venous congestion by 13.5 %. Conclusion. Endovascular interventions in patients with IC are associated with recovery of balance in MC processes.
Highlights
shifts has been especially valuable after endovascular interventions
MC was assessed by laser Doppler flowmetry in 37 patients
Restoration of main blood flow was associated with increased nutritional blood flow by 56.0 %
Summary
Многочисленные исследования продемонстрировали при данной патологии выраженные изменения микроциркуляции (МЦ) [1, 3, 5, 13]. В частности, показаны изменения микрососудов спастико-атонического характера с интенсификацией артериоло-венулярного шунтирования крови, ограничением нутритивного кровотока и формированием венозного застоя [3, 5].
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