Abstract
A new, facile, and efficient procedure for conjugate addition of indole and pyrrole with Michael acceptors have been developed for pulverization-activation reaction catalyzed by wet cyanuric chloride (2,4,6-trichloro-[1,3,5]-triazine or TCT) through grinding under solvent-free conditions at room temperature. Also, double-conjugate 1,4-addition of indoles to dibenzylidenacetones and conjugate addition of thiols with Michael acceptors using wet-TCT as catalyst is reported.
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