Abstract

<b>Kyrle's Disease: Hyperkeratosis Follicularis et Parafollicularis in Cutem Penetrans</b>. Presented byDr. Joseph Gropen. A 23-year-old Caucasian woman states that she noticed "bumps" appear on her legs and thighs when she was 9 years of age. Since that time more lesions gradually appeared, chiefly on the extensor surface of the legs and thighs and on the back. Within the past year lesions also appeared on the arms. They are asymptomatic and show no tendency towards spontaneous regression. The past history is noncontributory. No familial history of similar condition could be elicited. The single lesion represents a firm, slightly erythematous crateriform papule containing a central plug. The papules vary in size from that of a pinhead to a pea. There was no tendency to grouping. Treatment with vitamin A, 150,000 units per day, did not influence the clinical appearance of the lesions. Discussion Dr. Clete S. Dorsey: The

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