Abstract
As we all know, gene regulatory network is a kind of basic and important biological network. It can regulate and control the robustness of gene regulatory network through input, noise, parameters and positive and negative feedback. In this paper, we first briefly review the progress of gene regulatory network control, and then put forward some basic scientific issues related to control. The control of gene regulatory networks is based on life science and control theory. In the past few decades, the basic ideas and methods of cybernetics have gradually penetrated into the research of gene regulatory networks. At the same time, the control problems originating from life science have brought us new opportunities and challenges. The control of gene regulatory networks is a basic problem that plagues human beings in life science, such as the control of gene regulatory networks. It is of great practical significance to prolong life span, cure cancer, diabetes and other persistent diseases. In addition, the study of gene regulation network control has potential application value for the development of synthetic biology, network medicine, personalized medicine and other related disciplines.
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