Abstract
Extracts of the urine of rats, fed or injected intraperitoneally with indole-3-carboxylic acid, contained about 20% of the original acid, the corresponding glucuronide and 6-hydroxyindole-3-carboxylic acid. N-(Indole-3-carbonyl)glycine was synthesised and shown absent from the urine extracts. Oxidation of indole-3-carboxylic acid by Undenfriend's method gave the 5- and 6-hydroxy derivatives, indole, anthranilic acid and N-formylanthranilic acid.
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