Abstract

The requirement of three species of lactobacillus for acetate and its replacement by mevalonic acid was investigated. It was found that, in the presence of 1% glucose, Lactobacillus acidophilus had a requirement for sodium acetate which could be replaced by 1/8000 times its concentration of mevalonic acid, but when the glucose concentration was 2%, acetate was no longer required. Lactobacillus arabinosus also required acetate, but mevalonic acid replaced only partially the acetate requirement. Acetate was not required, under the present experimental conditions for Lactobacillus casei. The acetate requirement of L. acidophilus could also be replaced by β-hydroxy-β-methylglutaric acid and by 2,2′-dimethylacrylic acid, but not by farnesol or geraniol.

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