Abstract
The present study aimed to comprehensively assess if oats intake is beneficial for diabetic patients. The literature search was conducted in PubMed database up to 23 August 2015. Fourteen controlled trials and two uncontrolled observational studies were included. Compared with the controls, oats intake significantly reduced the concentrations of glycosylated hemoglobin A1c (HbA1c) (MD, â0.42%; 95% CI, â0.61% to â0.23%), fasting blood glucose (FBG) (MD, â0.39 mmol/L; 95% CI, â0.58 to â0.19 mmol/L), total cholesterol (TC) (MD, â0.49 mmol/L; 95% CI, â0.86 to â0.12 mmol/L), low-density lipoprotein cholesterol (LDL-C) (MD, â0.29 mmol/L; 95% CI, â0.48 to â0.09 mmol/L). Oatmeal significantly reduced the acute postprandial glucose and insulin responses compared with the control meal. The present study has revealed a beneficial effect of oats intake on glucose control and lipid profiles in type 2 diabetic patients. Further investigations of oats intake in patients with type 1 diabetes and the safety of oats consumption are required.
Highlights
Type 2 diabetes is a common chronic disease with great global health and economic burden
Oats are a good source of soluble dietary fiber rich in ÎČ-glucan, which is considered as a bioactive component in reducing postprandial glucose and insulin responses, improving insulin sensitivity, maintaining glycemic control and regulating blood lipids [4,5,6,7]
FBG, fasting blood glucose; PBG, postprandial blood glucose; FINS, fasting insulin; PINS, postprandial insulin; hemoglobin A1c (HbA1c), glycosylated hemoglobin; homeostasis model assessment-insulin resistance (HOMA-IR), homeostasis model assessment of insulin resistance; HOMA-B, homeostasis model assessment of ÎČ-cell function; ADA, American Diabetes Association; NA, not available; ONOG, organic naked oat with whole germ; GIB, glycemic index breakfast; GI, glycemic index; MBG, mean blood glucose; MDI, mean daily insulin. §, changes were statistically significant from baseline (p < 0.05); *, changes from baseline were significantly different between groups (p < 0.05); a p < 0.05, vs. usual care group; b p < 0.05, vs. diet group; c p < 0.05, vs. 50 g-ONOG plus diet group
Summary
Type 2 diabetes is a common chronic disease with great global health and economic burden. Oats are a good source of soluble dietary fiber rich in ÎČ-glucan, which is considered as a bioactive component in reducing postprandial glucose and insulin responses, improving insulin sensitivity, maintaining glycemic control and regulating blood lipids [4,5,6,7]. A modified diet with ÎČ-glucan from oats was reported to be superior to the American Diabetic Associationâs diet in improving metabolic and anthropometric profiles in well controlled type 2 diabetic patients: larger decreases in glycosylated hemoglobin A1c (HbA1c), weight and body mass index (BMI); greater increase in high-density lipoprotein cholesterol (HDL-C) [9]. The aim of this systematic review was to comprehensively evaluate if oats intake is beneficial for both the short-term glucose response and the long-term glucose control as well as other metabolic parameters such as lipid and anthropometric profiles in type 2 diabetic patients
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
