Abstract

AimRecent studies have provided evidence that enhanced stress level is associated with the increase of psychotic symptoms in both clinical and non-clinical populations. It has also been demonstrated that cognitive biases contribute to psychotic experiences. However, it remains unclear whether the effect of cognitive biases and perceived stress on psychotic-like experiences (PLEs) is influenced by coping methods. In the present study we examined whether the relationship linking cognitive biases with PLEs is mediated by the level of stress and whether particular coping methods modify the relationship between stress and PLEs.MethodsThe study sample consisted of 290 non-clinical subjects; study variables were assessed by questionnaires. Moderated mediation analyses were conducted.ResultsPerceived stress was found to serve as a partial mediator in the relationship linking attention to threat (ATB) and external attribution biases (ETB) with psychotic-like experiences. Also, moderated mediation analysis revealed that the indirect effect of attention to threat bias on positive and depressive symptoms of psychotic-like experiences via perceived stress was stronger at higher levels of distraction seeking coping. Moreover, the indirect effect of ATB on depressive symptoms was moderated by task-oriented coping and emotion-oriented coping. Task-oriented coping also moderated the indirect effect of ETB on depression.ConclusionThe findings imply that both perceived stress and coping styles are important factors affecting the association between cognitive biases and psychotic-like experiences.

Highlights

  • Cognitive biases have been recognized as important risk factors for various psychiatric conditions, including psychotic disorders

  • Perceived stress was found to serve as a partial mediator in the relationship linking attention to threat (ATB) and external attribution biases (ETB) with psychotic-like experiences

  • Moderated mediation analysis revealed that the indirect effect of attention to threat bias on positive and depressive symptoms of psychotic-like experiences via perceived stress was stronger at higher levels of distraction seeking coping

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Summary

Introduction

Cognitive biases have been recognized as important risk factors for various psychiatric conditions, including psychotic disorders. In line with the hypothesis of extended psychotic phenotype [1], the role of cognitive biases has been examined in samples of patients suffering from schizophrenia, individuals with ultrahigh risk for psychosis (UHR), and community samples with subclinical psychotic experiences. These studies differentiated specific cognitive biases, i.e. attributional bias [2,3,4], attention to threat bias [5, 6], threat anticipation [7], and jumping to conclusions [8, 9] which are involved in the psychotic symptoms development. The central role of stress has been widely investigated and well-replicated in samples of patients with schizophrenia [13, 14], first episode psychosis [15], UHR individuals [10, 16, 17], and healthy subjects with psychosisproneness [11, 18]

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