Abstract
The separation of germ and somatic cells is one of the oldest problems in developmental biology. In many animal species, a specialized portion of the egg cytoplasm, or germ plasm, is inherited by the cell lineage which gives rise to the germ cells, or germline. Germ plasm contains the maternal factors that are sufficient for germline formation. In Drosophila , germ plasm is referred to as polar plasm and is histologically distinguished by the presence of polar granules, which act as a repository for the maternal factors required for germline formation. We have been focusing on the function of two such factors, mitochondrial large rRNA (mtlrRNA) and nanos mRNA (for review, see Kobayashi, Sato and Hayashi, 2005).
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