Abstract

Recent studies show that taxanes resistances may be positively associated with overexpression of MRP protein,the change of β-microtuble,thus negatively associated with the expression of HER-2.The therapies which are specific to these targets will reverse or postpone the occurrence of drug resistance and provide more evidences on the better use of taxanes in clinic. Key words: Breast neoplasms; Antineoplastic agents; phytogenic; Drug resistance; neoplasm

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