Abstract

In the last 30-40 years, a new scientific direction has been formed, which is studying the effect of xenobiotics on the nonspecific resistance of the organism and the immune system immunotoxicology. The subject of immunotoxicology is the study of the effect on the immune homeostasis of xenobiotics: toxic chemicals (TCh), pharmacological agents and biological agents [1-3]. At the same time, damage to the immune system can be the result of both direct and indirect effects of xenobiotics and/or their metabolites. In addition, xenobiotics (or their metabolites) can develop an immune response with the formation of antibodies. It should be noted, and the possibility of modification of toxic compounds, as a result of which they acquire the properties of antigen. It is also possible the formation of antibodies to the complex toxicant-antigen [1-4].

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