Abstract

As the most efficient professional antigen presenting cell.dendritic cell and its role in immunity to mycobaeterium tuberculosis have been caught a growing concern.After the infection of mycobacterium tu-berculosis,immature dendritic cell integrates innate and adaptive immunity by capturing the microbial anti-gens,migrating from infected tissues to peripheral immune organs and presenting antigens to T,B lympho-cytes.Dendritic cell secretes cytokines such as IL-12 and IFN-γ,which regulate the immune system.Studv on the mechanisms of dendritic cell in immunity to mycobacterium tuberculosis provides basis for the develop-ment of novel anti-tuberculosis vaccine and immunotherapy. Key words: Dendritic cell; Mycobacteria tuberculosis; Immune response

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