Abstract

Long non-coding RNA(lncRNA)defined as ncRNAs of more than 200 nt in length.LncRNA is widely distributed and is involved in a variety of physiological and pathological processes of lung.In addition, lncRNA plays an important role in regulating the initiation and development of lung cancer.More details about mechanisms of lncRNA regulation of lung physiology and pathology are not clear.This review summarizes the mechanisms and current status of lncRNA associated with lung development and lung diseases, which provides insights in the relationship between lncRNA and respiratory system. Key words: Long non-coding RNA; Lung development; Lung injury; Regulation

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