The Mechanism of Action and Clinical Research Progress of Gastrodin in the Treatment of Vertigo

Abstract

Gastrodin is a phenolic glycoside with the chemical name of 4-hydroxybenzyl alcohol-β-D-glucopyranoside, which is the main bioactive component of Gastrodia in China. Gastrodin has low toxicity, good sedative and sleeping effects, can effectively dilate the body's blood vessels, increase myocardial blood flow, have a protective effect on the body's nerve cells, and play a role in regulating the excitation and inhibition of the cerebral cortex in the central nervous system, improving vestibular function, anti-inflammatory, antioxidant and other effects, thereby improving the clinical dizziness and other symptoms of patients. Gastrodin injection has good clinical effect in the treatment of vertigo, and no obvious adverse reactions have been observed. Compared with gastrodin alone in the treatment of vertigo, the combination with promethazine, diphenhydramine, betahistine and other drugs can effectively improve the treatment rate and reduce the incidence of related side effects.