Abstract

The mechanical association of chromosomal formation to patient age remains poorly understood. Previous studies have been unable to fully investigate the age-aneuploidy dynamic due to most aneuploidies being lethal to embryonic development prior to implantation. Comprehensive chromosomal screening (CCS) of blastocysts allows for previously unobtainable insight into the biology of aneuploidy. This study investigated aneuploidy in embryos derived from autologous oocytes to better understand the chromosome specific influences of patient age on the mechanisms of aneuploidy.

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