The measurement of corneal spherical aberration in the patients with cataract and the application in the choice of aspherical intraocular lens

Abstract

Objective To investigate the distribution of spherical aberration of anterior corneal surface in Chinese eyes with cataract and the related factors of spherical aberration for the choice of aspheric intraocular lens.Methods Spherical aberration of anterior corneal surface,asphericity Q value and average corneal curvature was measured with an iTrace wavefront analyzer in 572 Chinese patients (572 eyes) with cataract.Axial length measured by IOLMaster was recorded for each eye.To analysis the relationship between spherical aberration of anterior corneal surface and age,asphericity Q value,average corneal curvature,corneal astigmatism,axial length.Results Mean value of spherical aberration was (0.25 ± 0.08) μm for the central 6-mm zone.The spherical aberration was positively correlated with asphericity Q value,average corneal curvature and negatively correlated with axial length (P ＜ 0.05).No statistically significant correlation was found between spherical aberration and age,astigmatism(P ＞ 0.05).The influence of asphericity Q value(Beta =0.837,P ＜0.001) and average corneal curvature (Beta =0.250,P ＜0.001) were statistically significant in spherical aberration.The data were divided into three groups according to asphericity Q value(G1:-1 ＜ Q ＜ 0; G2:Q =0; G3:Q ＞ 0).The difference in spherical aberration among three groups was statistically significant (P ＜ 0.05).Conclusion There is significant interindividual variability in corneal spherical aberration.Corneal spherical aberration is correlated with asphericity Q value,average corneal curvature positively and axial length negatively.The influence of asphericity Q value and average corneal curvature are statistically significant.Accurate measurement of spherical aberration is necessary for the individualized choice of aspherical intraocular lens. Key words: Aberration, spherical; Lens, intraocular; aspherical ; Cornea