The mean velocity of posterior cerebral artery and basilar artery in Parkinson's disease with sleep disorders

Abstract

ObjectiveThe study aimed to assess the mean velocity of blood flow in the posterior cerebral artery and basilar artery in Parkinson's disease with sleep disorders in the neurology outpatient clinic of RSUP. Dr.Wahidin Sudirohusodo Makassar. MethodsThis study was conducted on Parkinson's patients with sleep disorders detected by using the Pittsburgh Sleep Quality Index (PSQI) score, Insomnia Severity Index (ISI), Epworth Sleepiness Scale (ESS). Subjects who experienced two disorders of the three scores performed a transcranial doppler examination to calculate the mean velocity of blood flow in the posterior cerebral artery and basilar artery. ResultsSeven subjects met the inclusion criteria with an average age (60.1±6.89 years), four male patients, and three female patients. The most significant score was PSQI showing mild to severe poor sleep quality (11.1±4.74) and the ESS score showing mild to moderate sleepiness (8.57±4.92). The mean velocity of blood flow decreased in the posterior cerebral artery and basilar artery. Posterior cerebral artery; PSQI scale; right (27.5±3.59), left (27.5±6.41), right ESS scale (28.7±3.30), left (27.6±9.29) basilar artery; PSQI and ESS scale (19.5±4.9). ConclusionParkinson's disease with sleep disorders in the PSQI and ESS scores show a decrease in the mean velocity of blood flow in the posterior cerebral artery and basilar artery. It is according to the supply of blood flow to substantia nigra pars reticularis and pons that play a role in non-motor symptoms of Parkinson's disease.