Abstract

BackgroundScaffolds are one of the three most important elements constituting the basic concept of regenerative medicine, and are included in the core technology of regenerative medicine along with stem cells and tissue engineering. Stem cells are very important technology because they are directly responsible for the regenerative treatment of the disease and the damaged tissue, but with regards to the technology and the products that use stem cells exclusively, there is a technical limitation of limited survival rate and the engraftment rate of the transplanted cell, and rather than recovering the damaged tissue fundamentally, there is a limit that the concept is more of just another medicine treatment using cells.A scaffold is a natural or synthetic biocompatible material transplanted into a human body to be used as the exclusive treatment or as an assisted method of another treatment of a disease and for the recovery of damaged tissue. Therefore, according to the characteristics of the tissue to be applied, scaffolds must have the characteristics such as the excellent biocompatibility, biodegradability, minimum immunity and inflammation, proper mechanical strength and interaction between the material and the cells.ResultsThe world stem cell market was approximately 2.715 billion dollars in 2010, and with a growth rate of 16.8% annually, a market of 6.877 billion dollars will be formed in 2016. From 2017, the expected annual growth rate is 10.6%, which would expand the market to 11.38 billion dollars by 2021. Meanwhile, the world scaffold element technology market was approximately 4.57 million dollars in 2013, and by increasing 13.4% annually, it is estimated to expand to 10.63 million dollars by 2020. The Korean scaffold element technology market was about 22 million dollars in 2013, and with a steady growth of approximately 13.4% every year, it is prospected to be about 52 million dollars by 2020.ConclusionsIn comparison to the medical material and medicine sales growth rate, the future scaffold element technology market is judged to be higher in growth possibility.

Highlights

  • Scaffolds are one of the three most important elements constituting the basic concept of regenerative medicine, and are included in the core technology of regenerative medicine along with stem cells and tissue engineering

  • In comparison to the medical material and medicine sales growth rate, the future scaffold element technology market is judged to be higher in growth possibility

  • Concept and characteristics of scaffolds Scaffolds are one of the three most important elements constituting the basic concept of regenerative medicine, and their role is adhesion and differentiation of the cells disseminated inside and outside of their structure, and the basis for providing the proper environment for cell proliferation and differentiation moving from the surroundings of the tissue and for providing the tissue form required [14]

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Summary

Introduction

Scaffolds are one of the three most important elements constituting the basic concept of regenerative medicine, and are included in the core technology of regenerative medicine along with stem cells and tissue engineering. A scaffold is a natural or synthetic biocompatible material transplanted into a human body to be used as the exclusive treatment or as an assisted method of another treatment of a disease and for the recovery of damaged tissue. Due to developments in technology and industry, there are increasing cases of defunctionalization or damage to tissues or organs from various accidents, diseases, and aging, and as the human body reaches its limits in self-regeneration ability, the need for proper and effective treatment methods is increasing rapidly [1,2,3]. Research is currently being done on stem cell differentiation within scaffolds and mechanisms of the tissue regeneration on transplant to the human body and efforts on the development and application of its therapeutic method [13]. It is very difficult to form three-dimensional artificial organ similar to the structurally complex tissue within the human body due to the technical limits in the biomaterial development

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