Abstract

Posttraumatic stress disorder (PTSD) has been a controversial diagnosis, with concerns including the sheer number of possible minimal diagnostic combinations (1,750), increasing to >10,000 theoretical possibilities in Diagnostic and Statistical Manual of Mental Disorders (5th ed.) proposals. This study examined whether the theoretical combinations postulated actually occur in a large sample of military personnel. The design of the study was a retrospective examination of PTSD checklists from 3,810 participants who, based on scores, endorsed symptoms consistent with probable PTSD. Combinations of PTSD Checklist–Civilian Version (PCL-C) symptom clusters were identified using data from active-duty military personnel who completed the 2005 and the 2008 Department of Defense (DoD) Health Related Behaviors Among Active Duty Military Personnel Survey. The study examined (a) occurrence of combinations, (b) unique minimum combinations, (c) most frequent combinations, and (d) replication of symptom combinations and clusters. The PCL-C scores showed 1,837 unique scoring combinations, 83.5% (1,533/1,837) of the observed unique scoring combinations occurred just once. The most frequently occurring combination (17/17 endorsed) accounted for 955 participants (25.1%), the second most frequent (16/17 endorsed) accounted for 75 participants (2.0%). PTSD most often presented as a unique constellation of symptom clusters, either capturing symptoms while allowing for considerable variability in its presentation, reflecting different severities of the disorder, or raising concerns about the classification itself, and any future classification that Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-V) might develop.

Highlights

  • Posttraumatic stress disorder (PTSD) has been a controversial diagnosis, with concerns including the sheer number of possible minimal diagnostic combinations (1,750), increasing to >10,000 theoretical possibilities in Diagnostic and Statistical Manual of Mental Disorders (5th ed.) proposals.This study examined whether the theoretical combinations postulated occur in a large sample of military personnel.The design of the study was a retrospective examination of PTSD checklists from 3,810 participants who, based on scores, endorsed symptoms consistent with probable PTSD

  • Proposed changes for PTSD in Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSMV) have potentially added to the confusion with new symptoms slated for inclusion

  • If PTSD has a true occurrence in the clinical world holding the entire symptom combinations theoretically argued, this reality would hold considerable sway to reconsider the ramifications of the classification schema in place and in any future proposals

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Summary

Introduction

Posttraumatic stress disorder (PTSD) has been a controversial diagnosis, with concerns including the sheer number of possible minimal diagnostic combinations (1,750), increasing to >10,000 theoretical possibilities in Diagnostic and Statistical Manual of Mental Disorders (5th ed.) proposals.This study examined whether the theoretical combinations postulated occur in a large sample of military personnel.The design of the study was a retrospective examination of PTSD checklists from 3,810 participants who, based on scores, endorsed symptoms consistent with probable PTSD. PTSD most often presented as a unique constellation of symptom clusters, either capturing symptoms while allowing for considerable variability in its presentation, reflecting different severities of the disorder, or raising concerns about the classification itself, and any future classification that Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-V) might develop. While other disorders hold numerous paths to cover possible presentations of a disorder (e.g., depression has 112 possible combinations, generalized anxiety disorder 20 combinations, etc.), no disorder in current psychiatric classifications contains this apparent diversity This problem of number and allowable combination of symptoms holds considerable concern for diagnostic utility, with such heterogeneity of symptoms making understanding about what we mean when someone is said to have PTSD nearly impossible. This study examined two large data sets of active-duty military personnel to determine the (a) occurrence of unique PTSD symptom combinations and (b) replication of symptom combinations and clusters

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