Abstract
This article analyses therapeutic adherence to the national health system from a multidimensional perspective, through a comparative analysis of regulation and planning at different levels of European, national, regional and corporate governance. This analytical path is oriented to identify the critical issues and possible strategies aimed not only to overcome them, but also to implement the current management through organizational tools and alternative management models. In this evolution, an important role is played by the funding deriving from the PNRR intended to implement both territorial medicine and digital innovation, as main axes of the path to improving therapeutic adhesion. The conclusions concern the application of organizational models ( one health, change management, value based health) able to channel these resources towards this area of therapeutic adherence. In the current phase of planning and financing from PNRR mission 6, italian institutions such as AGENAS and the Ministry of Health have initiated the reform of the D.M. n. 70/2015 through outline the lines of development of social protection to support social assistance adherence therapeutic. This programming path is accompanied by the regulation of local health care characterized by a greater continuity of care between hospital and home and multidisciplinary coordination for a wider take-up.
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