Abstract

The present study was designed to examine the anticonflict action of benzodiazepines injected into the mammillary body (MB) using the rat conflict-punishment procedure. Diazepam 20 μg/μl, chlordiazepoxide 60 μg/μl and midazolam 30 μg/μl, bilaterally injected into the MB, produced a significant increase in the punishment responses without changes in the unpunished responses. These findings have demonstrated for the first time that the MB could be potential site of antianxiety action of benzodiazepines.

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