The Making Evidence-Based Medicine Simple Series — Prognosis Module

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OPEN ACCESSJune 6, 2013The Making Evidence-Based Medicine Simple Series — Prognosis Module Michael Mojica, MD Michael Mojica, MD New York University School of Medicine Google Scholar More articles by this author https://doi.org/10.15766/mep_2374-8265.9440 SectionsAbout ToolsDownload Citations ShareFacebookTwitterEmail AbstractAbstractThe Making Evidence-Based Medicine Simple Series is an evidence-based clinical practice curriculum. It consists of six modules reviewing the articles types addressing the most common clinical questions (i.e., diagnosis, therapy, harm, prognosis, meta-analysis, and clinical decision rules). Each module reviews an article using the Users Guide to Medical Literature criteria for validity, results, and applicability. Each modules includes a PowerPoint presentation with a script, a video of the presentation with narration, a quiz with answers, tips for teaching the module, a blank review form, and a completed critical article review for the article reviewed in the module.The prognosis module reviews the appraisal of the validity, results, and applicability of a prospective cohort study of an Australian population with osteoporotic fractures. The study addresses the following clinical question: Do patients over 60 years of age with an osteoporotic fracture, when compared to age and gender matched controls and followed over time, have in increased risk of all-cause mortality? In addition, this module reviews the following critical appraisal skills: (1) determining the difference between a prognostic and risk factor, (2) distinguishing between prevalence and incidence, (3) defining and interpreting standardized mortality ratios, (4) interpreting Kaplan-Meier survival curves, and (5) identifying factors suggestive of causality versus association. Educational Objectives By the end of this session, learners will be able to: Differentiate between prognostic factors and risk factors.Identify study designs applicable to prognosis studies.Outline a prognosis question in population/patient, intervention/indicator, comparator/control, and outcome format.Understand the validity criteria for a prognosis study.Distinguish between measures of frequency (i.e., prevalence and incidence).Define and calculate person-years.Interpret absolute mortality rates and life years lost.Define and interpret standardized mortality ratios.Interpret Kaplan-Meier survival curves.Understand the principles and utility of univariable and multivariable analyses.Interpret confidence intervals for precision and statistical significance.Identify factors suggestive of causality versus association.Understand the applicability criteria for a prognosis study.Develop a clinical bottom line for a prognosis study. Sign up for the latest publications from MedEdPORTAL Add your email below FILES INCLUDEDReferencesRelatedDetails FILES INCLUDED Included in this publication: Authors Instructions - MESS Curriculum - Overview.pdf Authors Instructions - MESS Curriculum - Prognosis Module.pdf Critical Article Review - Mortality after Osteoporotic Fracture - JAMA - 2009.pdf Critical Article Review Form - Prognosis.doc EBM Teaching Tips - General Approach to the Modules.pdf EBM Teaching Tips - Prognosis.pdf Lecture Script - Prognosis Studies.pdf Lecture Slides - Prognosis Studies.pdf Lecture Slides - Prognosis Studies.ppt Quiz - Prognosis.pdf Quiz Answers - Prognosis.pdf Video Screencast - Prognosis.mp4 To view all publication components, extract (i.e., unzip) them from the downloaded .zip file. Download editor’s noteThis publication may contain technology or a display format that is no longer in use. Related The Making Evidence-Based Medicine Simple Series — Diagnostic Testing Module The Making Evidence-Based Medicine Simple Series — Therapy Module The Making Evidence-Based Medicine Simple Series — Harm Module The Making Evidence-Based Medicine Simple Series — Prognosis Module The Making Evidence-Based Medicine Simple Series — Meta-analysis Module The Making Evidence-Based Medicine Simple Series - Clinical Decision Rule Module Copyright & Permissions© 2013 Mojica. This is an open-access publication distributed under the terms of the Creative Commons Attribution-NonCommercial license.KeywordsClinical Decision RuleJournal ClubEvidence-Based MedicineHarmEvidence-Based PracticePrognosisMolecular Diagnostic TestingMeta-AnalysisTherapy Disclosures None to report. Funding/Support None to report. Loading ...