Abstract

Objectives: To quantify the Black/Hispanic disparity in COVID-19 mortality in the United States (US). Methods: COVID-19 deaths in all US counties nationwide were analyzed to estimate COVID-19 mortality rate ratios by county-level proportions of Black/Hispanic residents, using mixed-effects Poisson regression. Excess COVID-19 mortality counts, relative to predicted under a counterfactual scenario of no racial/ethnic disparity gradient, were estimated. Results: County-level COVID-19 mortality rates increased monotonically with county-level proportions of Black and Hispanic residents, up to 5.4-fold (≥43% Black) and 11.6-fold (≥55% Hispanic) higher compared to counties with <5% Black and <15% Hispanic residents, respectively, controlling for county-level poverty, age, and urbanization level. Had this disparity gradient not existed, the US COVID-19 death count would have been 92.1% lower (177,672 fewer deaths), making the rate comparable to other high-income countries with substantially lower COVID-19 death counts. Conclusion: During the first 8 months of the SARS-CoV-2 pandemic, the US experienced the highest number of COVID-19 deaths. This COVID-19 mortality burden is strongly associated with county-level racial/ethnic diversity, explaining most US COVID-19 deaths.

Highlights

  • Coronavirus disease 2019 (COVID-19) suddenly emerged as a major cause of mortality in 2020 for human populations around the world

  • Among rural counties with population sizes

  • Of the 192,954 COVID-19 deaths in the US observed in the 8month period, over 92% can be attributed to the county Black/Hispanic disparity gradient

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Summary

Introduction

Coronavirus disease 2019 (COVID-19) suddenly emerged as a major cause of mortality in 2020 for human populations around the world. In the US, it is widely known that the burden of COVID-19 mortality fell disproportionately on US counties and states with higher proportions of Black and/or Hispanic residents during the first stages of the US COVID-19 public health crisis. This has been shown, for example, in separate analyses of counties of 10 large cities [4], COVID-19 Mortality Disparity by Race/Ethnicity all nonmetropolitan counties [5], and 28 states and New York City [6]. An analysis of county-level COVID-19 mortality variation from the first waves of the US COVID-19 epidemic can provide insights into the preparedness of the US public health system to dynamically respond to a pandemic and can be utilized to inform the development and enhancement of equitable and effective local public health policy and actions

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