The magnetic resonance imaging findings and pathological features of angiomatous meningioma

Abstract

Objective To study and summarize the magnetic resonance imaging (MRI) findings and pathological features of angiomatous meningioma (AM) for improving the accuracy of the preoperative diagnosis. Methods The clinical characteristics, MRI findings, intraoperative findings and pathological features of 18 patients with AM diagnosed by histopathology were retrospectively analyzed. The clinical presentations, MRI appearances, pathological and immunohistochemistry features of AM were also evaluated. Results There were 18 cases in total, including 13 supratentorial tumors and 5 infratentorial cases; 3 cases beside cerebral falx, 7 cases convexity, 3 cases cerebellum, 2 cases cerebellopontine angle area, 2 cases sellar and 1 case sphenoid ridge. Most lesions were oval in shape. 13 cases showed significant peritumoral edema. Signal-void vessels could be found within or around the tumor in 14 cases. 5 tumors had necrosis and cystic areas. Most AM presented significant heterogeneous enhancement and 16 cases showed wide attachment, including 15 cases of dural tail sign. All tumors underwent complete resection. 7 cases were sent to conduct immunohistochemical examination, including 6 cases CD34+, 7 cases CD31+, 6 cases EMA+, 6 cases Vim+, 7 cases S-100-, 6 cases GFAP-. Proliferating cell nuclear antigen Ki-67 expression was <10 % in all 7 cases. Conclusion AM has some MRI features, which can improve accuracy of preoperative diagnosis, but it still needs to be confirmed by pathology and immunohistochemistry. Key words: Angiomatous meningioma; Magnetic resonance imaging; Pathology; Immunohistochemistry