Abstract

Madura foot is a deep mycosis commonly seen in tropical and subtropical countries such as India. It is caused by two groups of organisms, bacteria belonging to the group of Actinomycetes and the true mycetes named eumycetes. The incidence is more common in agricultural workers. Generally these lesions were present on foot & shows presence of induration, fibrosis and minimal discharge from sinuses. Though culture remains the gold standard diagnostic test histopathology plays important role in the early diagnosis and definitive treatment of these cases.

Highlights

  • Mycetoma is a chronic granulomatous disease of skin, subcutaneous tissue and bones that is present worldwide and is endemic in tropical and subtropical regions

  • As the disease has slow and relatively pain free progression, it is usually diagnosed at an advanced stage [2, 3]

  • We present a case of Madura foot, diagnosed on histopathology

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Summary

Introduction

Mycetoma is a chronic granulomatous disease of skin, subcutaneous tissue and bones that is present worldwide and is endemic in tropical and subtropical regions. Affected site by this infection is the foot and was described by Gill in Indian for the first time in Madura district in 1842, the name Madura Foot [1,2]. It is a slow growing infection presenting with characteristic symptomatic triad of swelling, draining sinuses and extrusion of colonial grains in the exudates. Histopathological examination showed dense infiltration by acute inflammatory cells in the form of microabscesses along with pale eosinophillic necrotic material with abundant lymphocytes, plasma cells, multinucleated giant cells and abundant septate, branching fungal hyphae (Fig3) Gram stain was negative. Fig-5: PAS stained section shows delineated septate hyphae of Eumycetes [PAS: 100X]

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