Abstract
Chicken anti mouse immunoglobulin antiserum (CαMIg) ∗ recognizes a cell surface molecule on several mouse T lymphomas. This molecule shares antigens with mouse immunoglobulins and appears to have a heavy and light chain, as determined by acrylamide gel electrophoresis. When used in immunofluorescence CαMIg also recognizes cells in sections of normal mouse lymphoid organs. It recognizes a few cells in the thymic cortex, all cells in the thymic medulla and all cells in the diffuse cortex of mouse lymph nodes. These cells are probably not B cells because they are not recognized by rabbit anti mouse immunoglobulin, which does recognize cells in lymph node follicles, known to be B cell domains. The cells recognized by CαMIg are also recognized by rabbit anti mouse thymocyte absorbed with nu/nu spleen cells, an antiserum specific in immunofluorescence for mouse T cell domains.
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