Abstract

AbstractHypercholesteremic rats were used to investigate the lipid depressant activities of lyophilized whole fish prepared from menhaden, silver salmon, mullet, and ocean perch. Ingestion of the whole fish supplements promoted a significant reduction in the circulating levels of cholesterol and phospholipids, and in the TC/TP ratios of blood lipids from the rat. The effects of whole fish were duplicated by feeding rats proportionate amounts of the oils found in these fish supplements. These supplements had similar, but less dramatic, effects on the liver lipids of the rats. The nonlipid components, isolated from the fish, had no apparent influence on the distribution of lipids in the blood and liver tissues. The preparations of lipid and nonlipid components of the fish are described, and the GLC analyses of marine oils are discussed.

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