Abstract
ObjectivesTo investigate the effectiveness of the Lifestyle Eating and Performance (LEAP) program for reducing health-related Quality of Life (QoL) symptoms in women with Polycystic Ovary Syndrome (PCOS). MethodsA retrospective chart review was conducted of PCOS clients seen by registered dietitians from a private group practice during 2010–2018. The in-vitro Leukocyte Activation Assay (LAA-MRT) was used to identify hidden non-immunoglobulin E (non-IgE) mediated food allergies and chemical sensitivities. The registered dietitians developed a patient-tailored oligoantigenic diet program for each subject.The LEAP program is an elimination diet built on the selection of less reactive food and chemicals based on the LAA-MRT results. A symptom survey was used to assess the QoL at the first visit and each follow-up visit. The severity of symptoms over the past month was recorded and quantified based on the frequency of the symptoms from a scale of 0 (low) to 4 (high) with a minimum score of 0 and a maximum of 248 points.Descriptive statistics were created and reported as means for continuous variables. Mixed model analysis of variance (ANOVA) was performed using R Studio Version 1.1.414. The study received Institutional Review Board (IRB) approval by California State University Sacramento. ResultsSubjects’ (n = 42) mean age was 35.2 years, and BMI was 34.4 kg/m2. The mean symptoms score at baseline was 72.5. After a personal eating plan was implemented based on the LAA-MRT results (mean 18.1 days following the plan), scores reduced to 29.3 (P < 0.001). The mean score at the second follow-up (mean 44.1 days) was 19.9 (P < 0.001), and at the third (mean 60.0 days) was 14.7 (P < 0.001). ConclusionsFindings from this pilot study highlight that a comprehensive, tailored dietary program can effectively achieve improvements in QoL for women living with PCOS. Funding SourcesThere was no funding for this research.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
