Abstract
Objective: Recurrent spontaneous abortion (RSA) occurs in 1–2% of the child bearing population. In the vast majority of cases, the etiology of RSA is unknown and several hypotheses have been made on the basis of available of data. Several studies have been reported that women with RSA manifest an abnormal cellular immune response with marked increase in peripheral blood NK cells with CD56+. Intravenous gamma immunoglobulin (IVIg) infusion is largely used as an effective means for treatment of some immune-related disease. And, some authors reported that elevated peripheral blood natural killer cells are effectively down regulated by IVIg infusion in women with RSA. In this study, we compared the preconceptional peripheral blood NK cells level in successful treatment outcome with that of the treatment failure group and evaluated the level of peripheral NK cells which was expected to successful treatment outcome using our low dose IVIG treatment protocol in patients with RSA.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
