Abstract
The Development of the atomic bomb has stimulated great interest in the study of ionizing radiation injury to living tissue. A large field experiment, designed to determine both physical and biological effects of the release of atomic energy, was successfully carried out by Joint Task Force One in Operation Crossroads in the summer of 1946 (1, 2). It is desirable to produce comparable ionizing radiation lesions in laboratory experiments not only to allow correlation with and better understanding of the data obtained at Bikini, but also to serve as a basis for future studies of ionizing radiation injuries. Previous work has largely concerned smaller forms. Some interest lies in studying larger animals, such as swine, not only from the standpoint of greater tissue masses and the increasing significance of depth dosage, but also because of a possible doser relation to the radiosensitivity of man. Groups of swine were given known amounts of total body irradiation with hard x-rays emanating from an industrial ...
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