Abstract
M etabolism comprises the network of interactions that provide energy and building blocks for cells and organisms, a network sustaining the living and allowing it to grow and reproduce. For well-studied organisms, especially microbes such as Escherichia coli, considerable information about metabolic reactions has been accumulated through decades of experimental work. This information, originally scattered through thousands of articles of original literature, has increasingly found its way into larger collections including encyclopedias [1] and online databases [2,3]. With easier availability of this information, it has become feasible to map the structure of large pieces of an organism’s metabolic network.
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