Abstract

The Kronos Longevity Research Institute (KLRI), founded in Jan., 2000, is a Phoenix-based not-for-profit institution conducting clinical translational research aimed at early detection and prevention of age-related diseases and slowing or reversing the aging process. KLRI also provides education in biomedical gerontology for regional and national professional and lay communities. KLRI is privately funded, mainly by the Aurora Foundation. S. Mitchell Harman, M.D., Ph.D., founding Director and President is board-certified in internal medicine and endocrinology and a former section chief and acting clinical director of the National Institute on Aging, NIH, with an international reputation as a leader in the field of hormones and aging. Other professional staff are: a Clinical Director, Director of Exercise Sciences, Senior Scientist, and Clinical Study Coordinator. KLRI's facility includes a clinical study center (CSC), an exercise study center (ESC), and a molecular laboratory. Current research focuses on relationships among aging, endocrine function, oxidative stress, and sarcopenia. All research projects are pre-reviewed by KLRI's Scientific Advisory Board, a distinguished group of biomedical investigators. KLRI sponsors a series of bimonthly seminars in Phoenix and an annual two-day national symposium, with talks on biomedical gerontology presented by world-renowned experts. The institute has plans to double faculty, staff, and research activities by 2006, which will require new sources of funding. The aging demography of the first half of the century will make KLRI's research increasingly relevant to the population of the U.S. and the world.

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