The Kidney Function in Relation to Drug Consumption in Patients with Rheumatoid Arthritis. (V)

Abstract

SummaryThe object of this work is to evaluate kidney function in patients with rheumatoid arthritis in relation to the total drug consumption (phenacetin and phenylbutazone consumption as well as gold salt and corticosteroid therapy) compared with the kidney function of other groups of patients in relation to phenacetin consumption.The material consists of 790 patients: 1) 244 patients with rheumatoid arthritis (165 women and 79 men) and 2) 546 patients with other diseases (328 women and 218 men). All the patients have been questioned about previous treatment and drug consumption. The information obtained is compared with the kidney function, which has been examined with 3 single 24-hour creatinine clearance tests. Clearance is corrected for surface. The material is statistically prepared.A short outline is given on the possible harmful effects of the medicaments mentioned on the basis of literature.There has not been found any relation between the kidney function expressed by clearance and the total drug...