Abstract
AbstractThe JenaLib database ("www.fli-leibniz.de/IMAGE.html":http://www.fli-leibniz.de/IMAGE.html) offers value-added information for all Protein Data Bank (PDB) and Nucleic Acid Database (NDB) entries. This includes:(1) atlas pages and entry lists, (2) PDB sequence information extracted from atomic coordinates, (3) PDB/UniProt sequence alignments that clearly indicate gaps, mutations, numbering irregularities and modified residues, (4) integration of data on single amino acid polymorphisms (SAPs), PROSITE motifs, exon structure and SCOP/CATH/Pfam domains with PDB, GO and taxonomy information, (5) display of these data in the sequence/alignment viewer and in the Jmol-based molecule viewer Jena3D ("jena3d.fli-leibniz.de":http://jena3d.fli-leibniz.de ); in the latter case both for asymmetric and biological units, (6) a QuickSearch option that allows searching for PDB/NDB code, UniProt ID/accession number and other search terms in one input field, (7) a sequence homology search (BLAST) and pattern search options and (8) SCOP/CATH/Pfam tree browsers.Offering all this information and analysis tools in one place makes JenaLib a unique resource for the dissemination of 3D structural information on biological macromolecules.
Highlights
Introduction and AimThe Jena Library of Biological Macromolecules (JenaLib) has served the scientific and educational communities since 1993
An automatized alignment between UniProt sequences and the sequences extracted from the Protein Data Bank (PDB) coordinates allows the mapping of any kind of sequence-based information onto 3D structures
Besides single amino acid polymorphisms (SAP) from the UniProtKB database and ProSite motifs exon and exonexon boundary information extracted from Ensembl and Pfam domains are mapped onto 3D structures
Summary
The Jena Library of Biological Macromolecules (JenaLib) has served the scientific and educational communities since 1993. It is a freely accessible internet resource aimed at a better dissemination of information on threedimensional biopolymer structures with an emphasis on visualization and analysis. It provides access to all structure entries at the Protein Data Bank (PDB) and the Nucleic Acid Database (NDB)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
