Abstract
To the Editor: Oh, the diabolical J-curve! Will we ever resolve this issue? Recently, you published a posthoc analysis1 of data from the Valsartan in Acute Myocardial Infarction Trial that showed, inter alia, that, after a myocardial infarction (MI), a sustained low blood pressure (BP; systolic BP <100 mm Hg on 2 of the post-MI visits at 1, 3, and 6 months) was a marker for bad cardiovascular outcomes. We were also told, incidentally, that this subset of patients had a significantly higher incidence of anterior MI and Q-wave MI and significantly higher maximum creatine kinase values during the MI than those who had normal BPs at 1, 3, and 6 months. In my view, these …
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