Abstract
In this study, it was investigated whether different concentrations of organophosphate insecticide chlorpyrifos (CPF) and systemic herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) on bovine liver catalase (CAT) activity cause any inhibitions or activations. For this purpose, 25, 50, 100, 250 and 500 ppm concentrations of CPF and 2,4-D were used. Following the applications of all tested concentrations of the both pesticides, the CAT activity elevated. Under the exposure of 25, 50, 100, 250 and 500 ppm concentrations, % CAT activity increases were calculated as 10.0; 6.2; 4.6; 6.9 and 6.0 in CPF apllications, while these increases were calculated as 13.1; 10.3; 17.0; 24.4 and 18.8 in 2,4-D applications, respectively. The present research indicated the elevations in CAT activity with 2,4-D were higher compared to CPF. This means that 2,4-D may have increased hydrogen peroxide production more than CPF.
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