The investigation of IOL with iris diaphragm implantation affected on corneal endothelium and anterior chamber angle

Abstract

Objective To infer the traumatic iris coloboma＇s treatment of IOL with iris dia- phragm implantation effectively and with fewer side effect. Methods Twenty cases with traumatic iris coloboma were studied. All patients were implanted an IOL with iris diaphragm after vitrectomy 3 months later. With the help of comeal endothelial microscopy and UBM, the changes of corneal endothelial cell density, anterior chamber depth and angle on preoperation and postoperation 1 week, 1 month and 3 months were observed. Results After operation, the density of corneal endothelial cells fallen, but the difference was not statistically significant between 1 week, 1 month, 3 months and pre-operation, and no difference after pairwise comparisons on 1 week, 1 month and 3 months. After operation, anterior chamber depth became shallow and angle narrow. The difference was statisti- cally significant compared with normal anterior chamber depth. Conclusions After operation, the density of corneal endothelial cell fallen, but the difference is not statistically significant compared with pre-operation. After operation, anterior chamber depth become shallow and angle narrow. The difference is statistically significant compared with normal anterior chamber depth. UBM can provide a non-traumatic method for the examination on anterior chamber depth and angle, and find out the early abnormal performance of anterior chamber angle, it is worth popularizing. Key words: IOL with iris diaphragm; Corneal endothelial cells; Anterior chamber depth; Anterior chamber angle; UBM