Abstract
Introduction Many researchers don’t believe in our works: they speak we are wrong when we evoke the Invertebrate Antibody...BUT: Discussion We have discovered, in the past, the sea star lymphocytes ( B and T sea star lymphocytes : cf Fig 1,2) : these cells of 4-5µ in diameter are smaller than Vertebrate lymphocytes And ...We discovered recently the IPA (Invertebrate Primitive Antibody) with the sea star IGKAPPA gene with IG sites (Meta Gene 2013). Therefore genomic data assert the evidence of primitive antibody in Echinodermata. Furthermore, we find MHC genes class I and class II in 2019 and Fab gene, Fc receptor gene in these Invertebrates
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