Abstract
Ever since Edward Jenner discovered the smallpox vaccine two centuries ago, immunization efforts have almost exclusively focused on activating the immune system. But when it comes to multiple sclerosis and other autoimmune disorders, researchers hope to switch off—rather than ramp up—the body's defenses. Even an automotive service mogul has taken the idea on board. Elie Dolgin investigates how the idea of vaccination is being turned on its head.
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