Abstract

Introduction: Intraoperative sentinel lymph node (SLN) analysis in breast cancer should be automated, concordant with histopathology and practical. One step nucleic acid amplification (OSNA), a highly sensitive validated intraoperative assay of cytokeratin 19 mRNA, is used for the detection of SLN macro- and micro-metastases in breast cancer. We present our 35 month data since introduction in December 2008.

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