Abstract
Properties of InterferonCells from several different classes of animals, including teleost fishes, have been shown to produce interferon.4,112 One interesting biologic property of interferon is its so-called "species specificity," a term that is probably a misnomer. Cross-reactivity between human and simian cells by heterologous interferons has been noted,113 and among a number of avian species there was considerable cross-reactivity within orders.114 It may therefore be more accurate to refer to family or order specificity. Nonetheless, it is true that, in general, interferon is most active in the cells of the same animal species that produce . . .
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