The interactive effect of habitual midday napping and nighttime sleep duration on impaired fasting glucose risk in healthy adolescents

Abstract

ObjectivesTo investigate the association between habitual midday napping and impaired fasting glucose (IFG), and the interactive effect of napping and time in bed (TIB) at night on IFG among healthy adolescents. MethodsThe sample comprised 625 early adolescents (12.26 ± 0.63 years old) who self-reported good health status from Jintan, China. Midday napping and nighttime sleep were measured using the Youth Self-report Sleep Questionnaire. Fasting plasma glucose was dichotomized into normal (<5.6 mmol/L) and impaired (≥5.6 mmol/L) levels. The multivariate random-effect logistic regression examined the nap-glucose relationship and the interaction between nap and TIB. Marginal effects of napping were calculated when TIB was held constant at different values. ResultsOf the participants, 83.20% (n = 520) took naps and 62.28% reported average nap durations ≥31 min in the past month. Moreover, 16% (n = 101) of participants had IFG. After adjusting for covariates, early adolescents who napped 3–4 days/week (OR = 1.72, p < 0.001), 5–7 days/week (OR = 1.34, p = 0.02) or ≥31 min/nap (OR = 1.52, 1.56, p's < 0.05) were associated with increased likelihoods of IFG compared to non-nappers. There was an inverse relationship between TIB and IFG among non-nappers (OR = 0.45, p = 0.03). Interaction analyses also showed significantly increased likelihoods of IFG only among nappers with TIB ≥9 hours. ConclusionThe relationship between midday napping and IFG is dependent on TIB. Midday naps may increase the risk for IFG among early adolescents who have sufficient nighttime sleep. However, further research is needed to confirm our preliminary findings.