Abstract
<p><strong>OBJECTIVE: </strong>The main objective of the study was to investigate the role of C-reactive protein on the relationship between Bisphenol A &amp; Cardiovascular Disease, where the C-reactive protein has been taken as a moderating variable.</p><p><strong>METHODS: </strong>Quantitative research design has been incorporated for evaluating the role of C-reactive protein. Similarly, non-parametric Spearman correlation test has been conducted to assess the relationship between BPA and CVD. The data was taken out from the National Health and Nutrition Examination Survey (NHANES), which was collected in the year 2009-2010.</p><p><strong>RESULTS: </strong>The impact of urinary Bisphenol A on serum C-reactive protein was found statistically significant according to the Spearman correlation coefficient, <em>r</em>s<em>= </em>.06, <em>p </em>= .015. The scatter plots found that there is no relationship between the two variables; this observation held true after filtering the outliers from the plot.</p><p><strong>CONCLUSION:</strong> The results might have positive change by contributing to the body of knowledge on bisphenol A and by rising scientific examination of substances used by the people in the daily life. Further research to identify other possible causes of CVD and elevation of CRP is recommended.</p>
Highlights
Bisphenol-A (BPA) is a synthetic substance used in polycarbonated plastic
The impact of urinary Bisphenol A on serum C-reactive protein was found statistically significant according to the Spearman correlation coefficient, rs= .06, p =
The results might have positive change by contributing to the body of knowledge on bisphenol A and by rising scientific examination of substances used by the people in the daily life
Summary
Bisphenol-A (BPA) is a synthetic substance used in polycarbonated plastic. BPA is mainly found in drinks, food packaging, and epoxy resin that are helpful in coating of cans within the food industry (Vogel, 2009). BPA is enclosed in an extensive variety of customers' products from the plastic container, baby bottles, and the lining of cans for beverages (Rochester, 2013, pp.132155). Numerous types of cardiovascular diseases including hypertension, angina, peripheral and coronary arterial disease and heart attack have been caused due to the concentration of higher urinary BPA in humans (Carwile et al, 2009). It has been observed in previous studies that the exposure of acute BPA usually supports the growth of arrhythmias in female rodent hearts (Gao & Wang, 2014). The progression of chronic kidney disease (CKD) among patients with primary hypertension can be caused by serum BPA (Hu et al, 2016, pp.332-337)
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