Abstract
1. The interaction of ANF and ANF(24–28)OH with the agonist, Isoprenaline (ISO), and the antagonist, Propranolol (PRO), of β-adrenergic receptor in the cardiovascular system in rat was investigated. 2. The studies showed that ANF and C-terminal fragment of ANF, ANF(24–28)OH, interfered with β-adrenergic receptor. 3. This does not exclude the action of this pentapeptide on the other receptors.
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