Abstract

We report the results of a retrospective study of the intensive care outcome of 196 children admitted with malignancy at a tertiary referral institution over a period of 10 years from 1988 to 1997. A total of 165 children required 196 admissions for a median of 3 days. Their mean age was 5.82 years and there were 100 boys (51%) and 96 girls (49%). Their admission median Apache II score was 18. A total of 150 children (76.5%) survived intensive care. Nonsurvivors had a higher Apache II score than survivors (23 vs 15 respectively, P < 0.001). Patients were divided into those needing postoperative care (n = 55), patients with respiratory infection (n = 39), systemic infection (n = 30), neurological complications (n = 20), respiratory failure with no evidence of infection (n = 17), metabolic effect (n = 13), tumour mass effect (n = 9), GI bleed (n = 5), cardiac failure (n = 4), post cardiac arrest (n = 3). The overall survival, defined as those who survived 1 week after discharge from PICU, was 73.4%. Invasive monitoring including arterial and central venous pressure line were inserted in 143 (72.9%), mechanical ventilation was required for 133 (67.8%), ionotropic support for 66 (33%), pulmonary artery floatation catheter insertion and monitoring in 23 (11.7%) and renal replacement therapy for 13 (6.6%) children. The profile of diseases in children admitted in PICU appears to be changing since last report from this unit in 1992 [1]. The most common reason for admission was need for postoperative care (28%) and survival in this group was 100%. There also is a significant improvement in survival rate of patients with systemic infections (63%) needing ventilatory support and children with respiratory (with or without infection) failure (67%) [2].

Highlights

  • In our experience, very often, even with a nonrebreathing mask (NRM), high oxygen delivery to patient with the existent materials is insufficient

  • TMSORG for R, C, N and Re were significantly associated with HM

  • P109 How we reduce allogenic blood transfusions in the patients undergoing surgery of ascending aorta D Radojevic, Z Jankovic, B Calija, M Jovic, B Djukanovic

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Summary

Introduction

Very often, even with a nonrebreathing mask (NRM), high oxygen delivery to patient with the existent materials is insufficient. There is evidence that increasing the dose of continuous renal replacement therapy (CRRT) is associated with improved survival in critically ill patients with acute renal failure (ARF) [1]. The aim of this study is to investigate if there is any difference in patients’ characteristics in ICU between COPD and nonCOPD diseases caused chronic respiratory failure and require mechanical ventilation during acute exacerbations. Noninvasive positive pressure ventilation (NPPV) has been reported to be beneficial in the treatment of acute exacerbation of chronic obstructive pulmonary disease (COPD), and to facilitate weaning In this trial we assessed the possible benefit of early NPPV in patients with blunt chest trauma and acute respiratory failure. The aim of this study was to compare the pharmacokinetic and pharmacodynamic parameters and the clinical efficacy of a continuous infusion of cefepime versus an intermittent regimen in critically ill adults patients with gram negative bacilli infection. The purpose of the study is to identify the factors associated with DNR status in our institution

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