Abstract

1Montreal Heart Institute, Montreal, Quebec; 2CIHR Institute of Circulatory and Respiratory Health, Ottawa, Ontario, Canada Correspondence: Ms Caroline Wong, CIHR Institute of Circulatory and Respiratory Health, 5000 Belanger St – S2580, Montreal, Quebec H1T 1C8, Canada. Telephone 514-593-7433, fax 514-376-7070, e-mail caroline.wong@icm-mhi.org Received for publication October 4, 2014, Accepted October 9, 2014 The Institute of Circulatory and Respiratory Health (ICRH) – 1 of the 13 Institutes of the Canadian Institutes of Health Research (CIHR) – supports research that focuses on cardiovascular health, respiratory health, blood and blood vessels, stroke, critical/intensive care, and sleep/circadian rhythms. Together, the disease areas that are covered under the mandate of the ICRH represent conditions with the largest health, societal, and economic burden of any of the other Institutes within CIHR. This reality and the extraordinary diversity of these medical conditions present a major operational challenge for the ICRH. Despite these difficulties and limited resources, the Institute’s 2013-2016 Strategic Plan1 demonstrates a commitment to ensuring that research excellence, capacity, competitiveness, innovation, and impact are enhanced across all research fields affiliated with the Institute. Moreover, building on previous successes, the ICRH continues to nurture past collaborations and work to establish new meaningful national and international alliances with the research community, partners, and other stakeholders to develop interdisciplinary, integrative health research that reflects Canada’s emerging health needs, gaps, and opportunities. The ICRH also strongly supports partnerships with relevant stakeholders to accelerate the transfer of new knowledge into benefits for Canadians. Notably, patient engagement is an important priority that will serve as 1 of the major building blocks of all clinically related initiatives of the ICRH. Based on identified gaps, opportunities, and feedback received from the International External Review Panel,2 ICRH research communities and partners, and in alignment with the CIHR 2014-2018 Strategic Plan, the ICRH identified 4 research priorities for 2013-2016. The first priority focuses on enhancing capacity, competitiveness, and impact of our communities through networking. This objective is consistent with the importance of aligning with CIHR’s largest comprehensive Roadmap Signature Initiative (RSI) the Strategy for Patient-Oriented Research (SPOR). In 2013, the Institute launched the ICRH Emerging Networks program in 3 gap areas, funding the Canadian Vascular Network, Canadian Respiratory Research Network, and the Canadian Stroke Prevention Intervention Network. In addition, through focused community development programs in critical care, stroke treatment and recovery, sleep and circadian rhythms, blood diseases, and resuscitation clinical research, the ICRH has targeted 5 additional research communities in need of networking. Aligned with CIHR’s Patient Engagement Framework,3 the ICRH will use specific actions and tools to enhance patient engagement in health research, implement patient engagement as a core priority in strategic initiatives, and offer programs that will allow patients to be true partners in research. Finally, the ICRH is continuing its collaboration with the National Heart, Lung, and Blood Institute of the National Institutes of Health in the ongoing support of 2 large Canada-US networks––the Resuscitation Outcomes Consortium and the Cardiothoracic Surgical Network, and will explore other international network opportunities. The second priority of the ICRH targets training, mentoring, and early career development to promote capacity-building––areas with an identified need. Recently, data have shown that the growth of funding within the ICRH’s mandated research areas has been slower than in all other areas at the CIHR, in particular for the cardiovascular and respiratory communities (Fig. 1A). Evidence suggests that this is primarily due to declining numbers of young investigators (Fig. 1B). The development of research capacity related to health systems/services and population/public health has been identified as requiring particular attention. In the upcoming years, the ICRH will work closely with relevant CIHR Institutes and various working groups to address this important and persistent capacity problem, focusing on training/mentoring issues and issues affecting the career success of young investigators. In 2014, the ICRH facilitated the development of the Emerging Research Leaders Initiative, which was launched as a joint initiative between the Heart and Stroke Foundation and the Canadian Lung Association––2 of the ICRH’s key partners. The ICRH will also continue its collaborative work with key stakeholders to develop a comprehensive training and mentoring strategy that will directly align with partner-led programs. A recent national ICRH survey (data not yet published) also confirmed the need for improved mentoring and the ICRH will work with its networks, partners, and the CIHR to improve the quality of mentoring based on current best practices. The third priority of the ICRH focuses on the expansion of clinical research opportunities, health systems/services research, and population health through cohort linkage and data enhancement. This initiative will provide Canadian scientists with a unique opportunity to boost knowledge development and translation at a fraction of the cost of developing new cohorts and will enable Canada to develop better population-based research, and design individualized and community-based prevention and intervention programs. In addition, this initiative will contribute to improving the potential for health and health systems research by creating a pool of population-based data that can be linked to Canada’s uniquely powerful administrative databases. Data enhancement and linkage will also directly assist in gathering and analyzing data related to Canada’s Aboriginal people and other vulnerable populations that are presently lacking. Finally, by helping to address issues such as data storage and access, this initiative will support research on ethics, and increase the use and sustainability of existing cohorts. Along with the CIHR and its other Institutes, the ICRH is helping to coordinate disparate and multidisciplinary communities to bridge gaps and identify ways for harmonizing and sharing population-relevant data sets and their efficient utilization. In the context of the increasing prevalence of cardiovascular and respiratory risk factors, many of which are also risk factors for other serious chronic diseases, this initiative provides a unique opportunity for the ICRH community to link with other research communities in building tools to fuel clinical research and population health, health services, and policy research. Through the Environments and Health Signature Initiative, the ICRH is coleading the Data Platforms component, COMMENTARy

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