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Abstract
Tricalciumphosphate (TCP) and hydroxyapatite (HA) have been suggested as bone graft substitutes in a wide range of applications. In this study, the initial stability of cemented acetabular cups was determined after reconstructing a combined cavitary and segmental defect in a realistic acetabular revision surgery model. The defects were reconstructed with mixes of TCP/HA particles and human bone grafts using the bone impaction grafting technique. In comparison with defect reconstruction with human bone grafts only, cup translation and tilt decreased by 27% when mixes of bone grafts and porous TCP/HA particles were used and by 55% when mixing the bone grafts with solid TCP/HA particles. Increasing the TCP/HA ratio within the mix significantly decreased cup translation. From a biomechanical perspective, mixes of TCP/HA particles and bone grafts are an attractive alternative for morsellized bone grafts when using the bone impaction grafting technique in the reconstruction of large defects of the acetabulum.
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