Abstract
The maximal responses (Emaxs) of isolated rat gastric fundus strips to 300 nm porcine galanin (Gal) were decreased in a concentration-dependent manner by terikalant (RP 62719). EC50of the agent equalled 4.39 μm (2.35–8.22). On the contrary the action of 30 n m of carbachol were not affected by the modulator in concentrations up to 30 μm. It is concluded that potassium currents may contribute to the modulation of Gal myotropic activity in the gut.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
