Abstract
BackgroundPrevious reports regarding health-related quality of life (HRQoL) of hypertensive individuals commonly concentrated on urban population. This study focused on rural population and aimed to explore the influencing factors of HRQoL.MethodsDate were derived from Henan Rural Cohort study. The HRQoL of participants were assessed via European Quality of Life Five Dimension Five Level Scale (EQ-5D-5L) instrument. Tobit regression model and generalized linear model were employed to explore the influencing factors of HRQoL. Another binary logistic regression was utilized to examine the robustness of our results.ResultsAmong 23,485 rural population, 8128 participants were identified with hypertension. The mean (SD) utility index and VAS score of non-hypertension group were 0.96 (0.09) and 79.66 (14.20), respectively, while in hypertension group were 0.94 (0.14) and 75.88 (15.50), respectively. Pain/discomfort was the most common self-reported problem (23.05%) for patients. Aging and suffering with other diseases were negatively associated with HRQoL among rural patients, while high socioeconomic status and healthy lifestyles corresponded with high HRQoL.ConclusionsHypertension did push considerable pressures on patients’ HRQoL. Maintaining healthy lifestyles and improving the socioeconomic status of patients were advisable ways to reduce this burden.Trial registration The Henan Rural Cohort Study has been registered at Chinese Clinical Trial Register (Registration number: ChiCTR-OOC-15006699). http://www.chictr.org.cn/showproj.aspx?proj=11375
Highlights
Previous reports regarding health-related quality of life (HRQoL) of hypertensive individuals commonly concentrated on urban population
EQ-5D instrument was more applicable for people in rural areas with low education status and it could provide a quantitative measure of health outcome [11]
Compared with non-hypertensive participants, participants with hypertension had following characteristics: men, lower education status, more proportion of unmarried/divorced/widowed, lower family average monthly income, lower physical activity, poorer sleep quality, and more probability to suffer from other non-communicable diseases (NCDs)
Summary
Study participants Subjects of this research came from Henan Rural Cohort study, a representative sample of rural population from Henan province in China. All permanent residents aged 18–79 years and without severe physical or mental disease were enrolled as study sample More details of this cohort were described in elsewhere [19]. Information sources and study variables In Henan rural cohort, basic information of participants including demographic characteristics, lifestyle factors, and history of diseases were obtained from a standard questionnaire. Sleep quality was evaluated via the Pittsburgh Sleep Quality Index (PSQI) and categorized into two categories as poor (PSQI > 5) and good sleep quality (PSQI ≤ 5) [21] Anthropometric measurements such as height and weight were measured by trained researchers. To assess the robustness of the results, participants were divided into health group (utility index = 1) and unhealth group (utility index < 1) [25], and the potential risking factors were detected by logistic regression model. Findings at P < 0.05 were regarded as significant
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