THE INFLUENCE OF USING THE NEEDLE ADAPTER TO REDUCE THE BIOMECHANICAL RISK FACTORS WITHIN HEMODIALYSIS ARTERIOVENOUS GRAFTS

Abstract

Hemodialysis vascular access failure is related to increased morbidity and mortality in hemodialysis patients, representing a challenging clinical problem which results in a high percentage of hospital entrance and an important economic burden on government's disbursement. In this paper, the feasibility of using the needle adapter to reduce the biomechanical risk factors within arteriovenous grafts is considered. The three-dimensional (3D) tapered 6 to 8 mm loop graft in the presence of venous and arterial needles with and without adapter was numerically simulated. Navier–Stokes equations for incompressible Newtonian fluid are the governing equation of this problem. k – ω two equations turbulence modeling were applied to capture flow features of low Reynolds turbulent flow regions in this simulation. The physiological velocity waveform was used as an arterial inlet boundary condition. The venose outlet boundary condition was a time dependent physiological pressure waveform. The results for the dialysis without the adapter demonstrated that the graft wall experiences increased hemodynamic stresses as a result of the hitting needle jet flow. The dialysis with the adapter demonstrated that the venous anastomosis experiences lower biomechanical risk factors in comparison to the dialysis without the adapter and it reduced the vascular access failure. Using adapter caused less damage to endothelial cells during hemodialysis.